ControlLabelSplit (Preclinical)
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**Purpose.** Split 5D image into **control** and **label** series, then compute mean difference.

Context I/O
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- **Reads:** ``Image`` with shape (X,Y,Z,NR,1)
- **Writes:** ``ImageCtr`` (X,Y,Z,NR), ``ImageLab`` (X,Y,Z,NR), ``ImageDif`` (X,Y,Z)

Parameters
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Key                Type / Default       Meaning
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``control_first``   bool / ``True``      If true, order is C,L,C,L,... else L,C,…
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YAML example
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.. code-block:: yaml

    modules:
      - name: ControlLabelSplit
        params:
          control_first: true